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作者观察了感染棉鼠丝虫的多乳鼠一次口服海群生500毫克/公斤后肝、脾、肾、肺和胸腔内的反应。观察项目包括微丝蚴粘着细胞、制动微丝蚴的出现以及微丝蚴密度的变化。1.对微丝蚴血症和成虫的作用:感染棉鼠丝虫的多乳鼠在治疗后1小时微丝蚴血症减少率为82.3%,治疗后24及72小时分别为98%及95%。治后微丝蚴血症的减少与治前的微丝蚴密度有关,治后1小时的微丝蚴血症减少率与治前血中微丝蚴密度之间存在反比关系。治疗后未见多乳鼠胸腔内成虫
The authors observed the reaction of multiple swine mice infected with the silkworm, Mice, with an oral dose of 500 mg / kg in the liver, spleen, kidney, lung and thorax. Observations included microfilamentous adherent cells, the appearance of immobilized microfilariae, and changes in the density of microfilariae. 1. Microfilaria and adults on the role of Microfilaria in mice infected with filariasis 1 hour after treatment microfilaremia reduced rate of 82.3% after 24 and 72 hours after treatment were 98% and 95 %. After treatment, microfilariaemia decreased with the treatment of microfilariae density before treatment, 1 hour after treatment microfilariaemia reduction rate and pre-treatment blood microfilariae density inversely proportional relationship. After treatment, no more adult rats in the thoracic cavity