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本文通过对确诊161例肝硬化患者的14项常用肝功能试验的评价,结果显示出血清γ球蛋白升高91例(82.73％)、总胆红素60例(67.42％)、锌浊82例(50.93％),而白蛋白降低77例(70.00％)。代偿期组和失代偿期组间比较有统计学意义:γ-球蛋白升高68.29％和91.13％(P<0.01)、总胆红素41.03％和88.00％(P<0.01)、锌浊32.88％和65.91％(P<0.01),而白蛋白降低43.90％和85.51％(p<0.01)。代偿期组和失代偿期组均值比较:γ-球蛋白升高27.8％和34.8％(p<0.01)、总胆红素1.6％和4.87％(P<0.01)、锌浊15.4％和17.4％(0.05>p>0.01),而白蛋白降低52.28％和42.29％(p<0.01),上述试验比其它试验有意义。四项试验总体均值95％可信限表明差异显著或非常显著。由此提出血清γ-球蛋白、白蛋白、总胆红素和锌浊对肝硬化的诊断和预后是有价值的。
The results of 14 commonly used tests of liver function in 161 cirrhotic patients confirmed that serum gamma globulin was elevated in 91 (82.73%), total bilirubin in 60 (67.42%), and zinc in 84 (50.93%), while albumin decreased 77 cases (70.00%). The compensatory group and decompensated group were statistically significant: γ-globulin increased 68.29% and 91.13% (P <0.01), total bilirubin 41.03% and 88.00% (P <0.01), zinc Turbidity 32.88% and 65.91% (P <0.01), while albumin decreased by 43.90% and 85.51% (p <0.01). Mean values of compensatory group and decompensated group were 27.8% and 34.8% (p <0.01), total bilirubin 1.6% and 4.87% (P <0.01), zinc turbidity 15.4% and 17.4% (0.05> p> 0.01) while albumin decreased by 52.28% and 42.29%, respectively (p <0.01). The 95% confidence limits for the overall mean of the four trials indicate significant or significant differences. It is suggested that serum γ-globulin, albumin, total bilirubin and zinc turbidity diagnosis and prognosis of cirrhosis of the liver is valuable.