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应用免疫组织化学方法，对３９例卵巢无性细胞瘤（ＤＧ）的凝集素受体（ＬＲ）、ｃ－ｅｒｂＢ－２蛋白的表达进行研究。结果发现ＤＧ能表达ＰＨＡ等１１种凝集素受体，不表达ＢＳＬ受体。其中ＰＨＡ受体在有浸润转移和无浸润转移ＤＧ中的表达有显著性差异（χ２＝７．７３，Ｐ＜０．０１）；ｃ－ｅｒｂＢ－２蛋白阳性者２３例（５８．９７％），ｃ－ｅｒｂＢ－２蛋白的表达在有浸润转移和无浸润转移ＤＧ之间有显著性差异（χ２＝４．４５，Ｐ＜０．０５）。上述结果提示：ＰＨＡ受体可作为判断ＤＧ浸润转移的参考指标；ＤＧ的发生和演进与ｃ－ｅｒｂＢ－２癌基因的启动有关，且ｃ－ｅｒｂＢ－２能预测ＤＧ的浸润转移倾向。
The expression of lectin receptor (LR) and c-erbB-2 protein in 39 cases of ovarian dysgerminoma (DG) was studied by immunohistochemistry. The results showed that DG can express 11 kinds of lectin receptor such as PHA, but not BSL receptor. Among them, the expression of PHA receptor in DG with or without invasive metastasis was significantly different (χ2 = 7.73, P <0.01); 23 cases with positive c-erbB-2 protein (58.97% The expression of c-erbB-2 protein was significantly different between infiltrating and non-infiltrating metastatic DG (χ2 = 4.45, P <0.05). The above results suggest that PHA receptor can be used as a reference index to judge the invasion and metastasis of DG. The occurrence and evolution of DG are related to the initiation of c-erbB-2 oncogene. C-erbB-2 can predict the invasion and metastasis of DG.