论文部分内容阅读
本文报道由作者建立的薄层色谱法,样品在硅胶薄层板上展开后,以苯芴酮显色,再在碘钨灯下照射可使锗-132衍生成荧光化合物,从而可用原位荧光扫描(外标法)定量,已用于倍半氧双羧乙基锗(锗-132)原料和制剂的含量测定及稳定性研究。经3批原料、9批注射液、3批口服液样品的222个测试数据统计,C.V.值为2.29%,同板的C.V.值为1.5%～2.7%(n=7～10);加样回收率101.5%,最低检出限为0.12μg。
This article reports the thin layer chromatography established by the author. After the sample is developed on a thin layer of silica gel, it is developed with benzofluorenone and irradiated with iodine tungsten lamp to derivatize germanium-132 into a fluorescent compound, which can be used for fluorescence in situ Scanning (external standard method) has been used to determine the content and stability of the raw materials and preparations of sesquioxybacryl ethyl germanium (germanium-132). The results of 222 test data of 3 batches of raw materials, 9 batches of injection and 3 batches of oral solution showed that the CV value was 2.29% and the CV value of the same plate was 1.5% -2.7% (n = 7-10) The rate was 101.5% with the lowest detection limit of 0.12μg.