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目的：探讨乳过氧化物酶系统在口腔微生态环境中对链球菌族生长和菌种平衡的影响。方法：将血型链球菌３４和变形链球菌Ｉｎｇｂｒｉｔ（ｃ）分为纯培养和混合培养等实验组，用连续培养方法，给予乳过氧化物酶（ＬＰＯ）、硫氰酸盐、Ｈ２Ｏ２，采用活菌计数法检测两菌的生长状态。结果：血型链球菌３４在参入乳过氧化物酶因素的培养液中，其生长量较为平稳，有较强的抵抗力，而变形链球菌的生长量显著下降；混合培养中两菌的生长量均有所提高。结论：两菌的共生可以提高它们对乳过氧化物酶系统的抵抗力；血形链球菌ＬＰＯ系统的高抵抗力与其在早期牙菌斑中占优势是相一致的。
Objective: To investigate the effect of lactoperoxidase system on the growth and bacterial balance of streptococci in oral microenvironment. Methods: Streptococcus mutans 34 and Streptococcus mutans Ingbrit (c) were divided into two groups: pure culture and mixed culture. Lactoperoxidase (LPO), thiocyanate and H2O2 were given by continuous culture method. Bacterial count method to detect the growth status of two bacteria. RESULTS: Streptococcus mutans 34 grew steadily and strongly in the culture medium with lactoperoxidase, while the growth of Streptococcus mutans decreased significantly. The growth of two strains in mixed culture Have improved. Conclusion: The symbiosis of the two bacteria increases their resistance to the lactoperoxidase system; the high resistance of the S. spp LPO system is consistent with its predominance in early dental plaque.