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INTRODUCTIONrnAccording to the demographics,the world population over 60 years will double from 605 million to 2 billion people between 2000 and 2050.Aging is a complex process in which the organism and its ability to respond to extal stresses become progressive decline.The degenerative aging process is the major underlying cause for aging-related diseases,including hypertension,diabetes,neurodegenerative diseases,cancer and so on [Table 1].