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目的:探讨北方地区蝮蛇咬伤引起DIC样综合征的临床表现及预后情况。方法:对2010-06-2011-09来本院就诊的97例蝮蛇咬伤病例进行回顾性分析,对其中确诊为DIC样综合征的9例病例进行血小板计数及凝血系统指标D-二聚体、血浆凝血酶原时间、活化部分凝血活酶时间、血浆纤维蛋白原及凝血酶时间检测及分析。结果:北方地区蝮蛇咬伤后DIC样综合征的发生率约为9.3%;9例患者分别于伤后1～8d内出现DIC现象,持续时间约2～7d,均无临床DIC表现。结论:北方地区蝮蛇咬伤可引起患者凝血及纤溶系统异常,出现DIC样综合征。
Objective: To investigate the clinical manifestations and prognosis of DIC-like syndrome caused by Viper bites in northern China. Methods: A retrospective analysis was performed on 97 cases of Viper bites from 2010-06 to 2011-09 in our hospital. Nine cases diagnosed as DIC-like syndrome were analyzed for platelet count and coagulation index D-dimer Body, prothrombin time, activated partial thromboplastin time, plasma fibrinogen and thrombin time detection and analysis. Results: The incidence of DIC-like syndrome in the northern region after viper snake bite was 9.3%. There were no clinical manifestations of DIC in 9 patients with DIC within 1 to 8 days after injury. The duration of DIC was about 2 to 7 days. Conclusion: Viper bites in northern China may cause abnormal coagulation and fibrinolysis in patients with DIC-like syndrome.