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目的:探讨丙氨酰-谷氨酰胺联合柴芍承气汤对重症急性胰腺炎的治疗效果.方法:72例重症急性胰腺炎患者,随机分为对照组和治疗组,各36例.对照组采用常规治疗,治疗组在常规治疗的基础上加用谷氨酰胺和柴芍承气汤,治疗结束后检测两组均检测各项生化指标,治疗结束后进行对比并做统计学分析.结果:治疗组的D-二聚体(4.6±1.9vs8.1±2.5)、白细胞(9.5±3.2vs16.3±4.9)、血淀粉酶恢复正常时间(4.1±1.9vs8.6±2.7)以及腹痛缓解(2.8±0.7vs4.7±0.8)、腹水消失时间(8.2±1.5vs15.3±2.4)、住院时间(21±7.4vs34±12.6)均少于对照组,且两组有显著性差异(P<0.05);并发症和死亡率与对照组无统计学差异(P>0.05).结论:对于重症急性胰腺炎患者在常规治疗的基础上,使用丙氨酰-谷氨酰胺与柴芍承气汤有较好疗效.
Objective: To investigate the therapeutic effect of alanyl-glutamine combined with Chaishao Chengqi Decoction on severe acute pancreatitis.Methods: Seventy-two patients with severe acute pancreatitis were randomly divided into control group and treatment group, 36 cases in each group.Control group The patients in the treatment group were treated with glutamine and Chaishaochengqi Decoction on the basis of routine treatment, and the biochemical indexes were detected in both groups after the treatment was finished.After the treatment, comparison was made and statistical analysis was made.Results: D-dimer (4.6 ± 1.9 vs 8.1 ± 2.5), white blood cells (9.5 ± 3.2 vs. 16.3 ± 4.9), and blood amylase recovery time (4.1 ± 1.9 vs 8.6 ± 2.7) in treatment and remission of abdominal pain (2.8 ± 0.7 vs 4.7 ± 0.8), ascites disappearance time (8.2 ± 1.5 vs 15.3 ± 2.4) and hospitalization time (21 ± 7.4 vs 34 ± 12.6), respectively. There was a significant difference between the two groups <0.05). There was no significant difference in complication and mortality between the two groups (P> 0.05) .Conclusion: For patients with severe acute pancreatitis, alanine-glutamine Soup has a good effect.