A new alkylene dihydrofuran glycoside with antioxidation activity from the root bark of Morus alba L

来源 :Chinese Chemical Letters | 被引量 : 0次 | 上传用户:ppasu
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A new alkylene dihydrofuran glycoside(1) was isolated from the root bark ofMorus alba L.,along with moracin M-3′-O-β-D-glucopyranoside (2),and moracin M-6,3′-di-O-β-D-glucopyranoside(3).Compound 1 was identified as 2-methylene-3-methoxy-2, 5-dihydrofuran-4-O-β-D-glucopyranoside on the basis of chemical and spectroscopic data including 1D and 2D NMR spectral analysis.In addition,the antioxidant activity of 1 was evaluated using the 1,1-diphenyl-2-picrylhydrazyl(DPPH) and 2,2′-azinobis- 3-ethylbenzothiazoline-6-sulphonic acid(ABTS) assay.The IC_(50) values were 2.49 and 0.45 mg/mL,respectively. A new alkylene dihydrofuran glycoside (1) was isolated from the root bark of Morus alba L. along with moracin M-3’-O-β-D-glucopyranoside (2), and moracin M-6,3’-di-O -d-glucopyranoside (3). Compound 1 was identified as 2-methylene-3-methoxy-2, 5-dihydrofuran-4-O-β-D-glucopyranoside on the basis of chemical and spectroscopic data including 1D and 2D NMR spectral analysis. In addition, the antioxidant activity of 1 was evaluated using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2’-azinobis-3-ethylbenzothiazoline-6-sulphonic acid IC_ (50) values ​​were 2.49 and 0.45 mg / mL, respectively.
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