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目的：探讨Ａ型肉毒杆菌毒素（ＢＴＸＡ）治疗面肌痉挛（ＨＦＳ）的疗效及副作用。方法：对２３５例ＨＦＳ病人进行面肌多点注射ＢＴＸＡ，对治疗前后的病情分级进行比较，并随访１２—３６周。结果：ＢＴＸＡ治疗的总有效率为９８．３％（２３１／２３５），无全身反应，半年复发率为６０％，药效作用时间平均１６周；重复注射同样有效。结论：局部注射ＢＴＸＡ是治疗ＨＦＳ的一种有效手段。
Objective: To investigate the efficacy and side effects of botulinum toxin type A (BTXA) in the treatment of hemifacial spasm (HFS). Methods: A total of 235 patients with HFS underwent multifocal injection of BTXA. The grades of patients before and after treatment were compared and followed up for 12-36 weeks. Results: The total effective rate of BTXA treatment was 98.3% (231/235). There was no systemic reaction. The half-year recurrence rate was 60% and the effective duration of treatment was 16 weeks. Repeated injection was also effective. Conclusion: Local injection of BTXA is an effective treatment for HFS.