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目的了解深圳市疑似预防接种异常反应分布特征,评价深圳市疑似预防接种异常反应监测系统整体运行情况。方法通过国家疑似预防接种异常反应信息管理系统收集深圳市2009-2012年监测个案数据,采用描述性分析方法进行流行病学分析。结果深圳市2009-2012年共报告AEFI个案3 626例,报告估算发生率为8.09/10万剂~20.53/10万剂;其中一般反应2 298例(63.28%)、异常反应1 074例(29.62%)、偶合症250例(6.89%)、心因性反应3例(0.08%)、待定1例(0.03%);监测系统个案完整率100.00%,及时报告率98.65%;需调查病例1 928例,调查率为100.00%,48 h内及时调查率为99.99%。结论深圳市疑似预防接种异常反应监测系统运转良好,但需进一步提高信息化管理水平,同时配合培训和督导,以期能够进一步提高监测敏感性。
Objective To understand the distribution of the abnormal response of suspected vaccination in Shenzhen and to evaluate the overall operation of the surveillance system of suspected abnormal vaccination in Shenzhen. Methods The data of monitoring cases from 2009 to 2012 in Shenzhen were collected through the national information system of suspected anaphylaxis vaccination, and the descriptive analysis was used for epidemiological analysis. Results A total of 3 626 AEFI cases were reported in Shenzhen from 2009 to 2012, with an estimated incidence of 8.09 / 10 000 to 20.53 / 10 000 doses. Among them, 2 298 (63.28%) were general reactions and 1 074 (29.62) were abnormal reactions (P0.05). The completeness rate of case monitoring system was 100.00% and the timely reporting rate was 98.65%. The number of cases requiring investigation was 1 928 (6.8%), three cases of cardioresistance (0.08%) and 1 case For example, the investigation rate was 100.00%, and the timely investigation rate within 48 hours was 99.99%. Conclusion The surveillance system for suspected anaphylaxis in Shenzhen is working well. However, it is necessary to further improve the level of information management. At the same time, it should cooperate with training and supervision so as to further improve the sensitivity of surveillance.