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目的分析我院2010年收集的药品不良反应报告,旨在了解不良反应发生的特点和规律,促进临床合理用药。方法对2010年上报的335例报告就ADR分布与年龄、给药途径、药物分类、累及系统及器官等方面进行回顾性统计分析。结果报告人中有医师327人,占总人数的97%;抗感染药物所占比例最大,占总例数的58.8%;儿童患者共96例,占总例数的28.65%;主要以静脉滴注方式给药;临床表现主要以胃肠道反应、变态反应为主。结论应重视和加强不良反应的监测上报工作,及时向临床反馈,提高安全用药意识,减少或避免不良反应的发生。
Objective To analyze adverse drug reaction reports collected in our hospital in 2010 in order to understand the characteristics and laws of adverse reactions and to promote rational drug use in clinical practice. Methods A retrospective statistical analysis was conducted on 335 cases reported in 2010 on ADR distribution and age, route of administration, drug classification, involved systems and organs. Results There were 327 physicians in the report, accounting for 97% of the total; the proportion of anti-infective drugs was the largest, accounting for 58.8% of the total number of cases; 96 pediatric patients, accounting for 28.65% of the total number of cases; Note injection; clinical manifestations mainly gastrointestinal reactions, allergic reactions. Conclusions Should pay attention to and strengthen the monitoring and reporting of adverse reactions, timely feedback to the clinic to improve awareness of safety medication to reduce or avoid the occurrence of adverse reactions.