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庆大霉素引起急性肾功能衰竭,国内罕见报告,我院曾收治1例,特报道如下。病例报告魏某,男,4岁7个月,住院号162411。因发热、咽痛拟诊急性扁桃体炎,于1980年11月16日开始应用庆大霉素80rag,每日1次肌注,共2天(每天5.3 mg/kg),第3天静脉滴注30mg(总量190mg)。患儿于首次用药后48小时开始尿量明显减少,并迅速出现尿闭,全身轻度浮肿、恶心、呕吐,于11月19日急诊住院。过去无肾脏病史。体检:T36℃。P90次/分,R28次/分,BP100/65mmHg。发育正常,营养中等,神志清楚,精神较差,呈急性病容。全身皮肤轻度浮肿,
Gentamicin caused acute renal failure, rare domestic report, our hospital had admitted 1 case, especially reported as follows. Case report Wei, male, 4 years and 7 months, hospital number 162411. Due to fever, sore throat diagnosed acute tonsillitis, began November 16, 1980 gentamicin 80rag, intramuscular once a day for 2 days (5.3 mg / kg per day), the first three days of intravenous drip 30 mg (total 190 mg). Children in the first 48 hours after the start of medication significantly reduced urine output, and rapid urinary tract obstruction, mild body edema, nausea, vomiting, November 19 emergency hospitalization. No history of kidney disease in the past. Physical examination: T36 ℃. P90 beats / min, R28 beats / min, BP100 / 65mmHg. Normal development, moderate nutrition, conscious, poor spirit, was acute disease. Systemic skin mild edema,