S5A-3 Increased Blood Pressure Variability Impairs Memory in Rats

• 作 者: ZHU Chao DU Ning-ning ZHOU Yan
• 机 构: InstituteofPharmacology
• 出 处: 神经药理学报
• 发表日期: 2018年4期
• 关键词: blood pressure VARIABILITY sinoaortic DENERVATION MEMORY CHOLINERGIC α7 NICOTINI
• 基金项目: This work was supported by the Natural Science Foundation of Shandong Province of China(ZR2014HQ007,ZR2017MH048),the Foundation of Overseas Distinguished Taishan Scholars of Shandong Province of China

Background and Objective:Increased blood pressure variability(BPV),which has been considered to cause brain damage,can be induced by sinoaortic denervation(SAD)in rats.This study was designed to test the hypothesis that increased BPV impairs learning and