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目的：观察维生素Ｋ３治疗高血压病的疗效。方法：２８例高血压病人（男性２１例，女性７例；年龄５５±ｓ１１ａ）交叉肌内注射维生素Ｋ３８ｍｇ和维生素Ｂ１１００ｍｇ各１次，观察用药前后３ｈ内的血压变化，其中１０例应用动态血压监测评价。结果：用维生素Ｋ３１．５ｈ时血压较用药前下降幅度与维生素Ｂ１相比差别非常显著（收缩压前者下降４．０±２．５，后者增加０．１±１．８ｋＰａ，Ｐ＜０．０１；舒张压前者下降２．４±１．８，后者增加０．３±１．４ｋＰａ，Ｐ＜０．０１）。结论：维生素Ｋ３降压有效，适用于伴发鼻出血，胆、肾绞痛的高血压病人
Objective: To observe the efficacy of vitamin K3 in the treatment of hypertension. Methods: Twenty-eight hypertensive patients (21 males and 7 females; age 55 ± s11a) were intravitreally injected with vitamin K38mg and vitamin B1100mg once daily to observe the change of blood pressure within 3 hours before and after treatment. Among them, 10 cases were monitored by ambulatory blood pressure monitoring Evaluation. Results: When vitamin K31.5h was used, the decrease of blood pressure before treatment was significantly different from that of vitamin B1 (the former decreased by 4.0 ± 2.5 and the latter increased by 0.1 ± 1.8kPa, P <0. 01; diastolic blood pressure decreased 2.4 ± 1.8, the latter increased 0.3 ± 1.4kPa, P <0.01). Conclusion: Vitamin K3 is effective in lowering blood pressure and is suitable for hypertensive patients with epistaxis, gall bladder and renal colic