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目的探讨应用长托宁联合血液灌流对治疗重度有机磷农药中毒患者的临床疗效。方法选择我院2006年5月至2008年5月收治的41例有机磷农药中毒患者,将其随机分为治疗组(A组21例)和对照组(B组20例)。A组在行长托宁为主治疗的同时联合血液灌流治疗,B组以常规阿托品治疗为主。结果两组患者神志清醒时间、ChE活性恢复时间、住院时间、治愈率、死亡率进行对比,治疗组均优于对照组(P<0.05)。结论长托宁联合血液灌流治疗重度有机磷农药中毒是一种良好的方法。
Objective To investigate the clinical effect of combination of penehyclidine and hemoperfusion on patients with severe organophosphorus pesticide poisoning. Methods Forty-one patients with organophosphorus pesticide poisoning admitted to our hospital from May 2006 to May 2008 were randomly divided into treatment group (21 cases) and control group (20 cases). Group A was treated with hemodialysis combined with hemodialysis while Governor Trowin was the main treatment, while Group B was treated with conventional atropine. Results Conscious time, ChE activity recovery time, hospitalization time, cure rate and mortality of two groups were compared, the treatment group were better than the control group (P <0.05). Conclusions Long-Tropinel combined with hemoperfusion is a good method for the treatment of severe organophosphorus pesticide poisoning.