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我所1995年1月至1998年1月应用纳洛酮静脉注射抢救急性海洛因中毒20例,成功18例,死亡2例,现报道如下。1临床资料1.1 一般资料 20例中,男18例,女2例;年龄16～43岁。1.2临床表现20例均有昏迷、发绀、呼吸抑制。19例肢体湿冷、瞳孔缩小:1例瞳孔散大;5例有脑水肿征象;5例有肺水肿征象;呼吸≤10次/分8例,11～12次/分12例;低血压8例;心律失常4例;5例尿潴留;4例潮式呼吸。20例下肢、手背及肘静脉等周围静脉有新旧注射痕迹。尿液定性检测查到海洛因。既往有心脏病史1例、胃病史4例。
Our January 1995 to January 1998 naloxone intravenous rescue of acute heroin poisoning in 20 cases, the success of 18 cases, 2 patients were killed, are reported below. 1 Clinical data 1.1 General Information 20 cases, 18 males and 2 females; aged 16 to 43 years. 1.2 Clinical manifestations of 20 patients have coma, cyanosis, respiratory depression. 19 cases of wet and cold limbs, miosis: 1 case mydriasis; 5 cases of signs of cerebral edema; 5 cases of signs of pulmonary edema; respiratory ≤ 10 beats / min 8 cases, 11 to 12 beats / min 12 cases; 8 cases of hypotension ; Arrhythmia in 4 cases; 5 cases of urinary retention; 4 cases of tidal breathing. 20 cases of lower extremity, dorsal and elbow vein and other peripheral vein with old and new injection marks. Qualitative urine test found heroin. Previous history of heart disease in 1 case, stomach history in 4 cases.