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目的:分析2008年度120例住院患者与400张处方抗菌药物使用情况,为临床合理使用抗菌药物提供参考。方法:根据《抗菌药物临床应用指导原则》及《围手术期病人预防使用抗菌药物合理性评价标准》,采用Excel电子表格对门诊和住院患者抗菌药物的使用情况进行分析。结果:住院患者抗菌药物使用率较高,尤其围手术期患者使用率达100.00%,其中预防性用药为90.00%,术前2h用药35.00%,术后用药63.33%,用药时间超过10d的43.33%。住院患者使用抗菌药物以喹诺酮类最高,头孢菌素类次之;门诊患者以大环内酯类抗菌药物最高,头孢菌素类次之。结论:抗菌药物应用不合理,应加强对抗菌药物临床应用的管理,必要时采取干预措施与药敏试验,促进临床合理使用抗菌药物。
OBJECTIVE: To analyze the use of antibacterials in 120 inpatients and 400 prescriptions in 2008, and provide a reference for the rational use of antibacterials in clinic. Methods: According to the Guiding Principles of Clinical Application of Antibacterials and Evaluation Criteria of Antibiotics Preventive Use in Perioperative Period, the use of antibacterials in outpatients and inpatients was analyzed by Excel spreadsheet. Results: The usage rate of antibacterials in hospitalized patients was high, especially in perioperative period. The rate of perioperative patients was 100.00%, including 90.00% for prophylaxis, 35.00% for 2h before operation, 63.33% for postoperative medication and 43.33% for 10d, . Inpatient use of antibiotics to quinolones highest, followed by cephalosporins; Outpatient macrolide antibacterials highest, followed by cephalosporins. Conclusion: The application of antimicrobial agents is not reasonable. The management of clinical application of antimicrobial agents should be strengthened. If necessary, interventions and drug sensitivity tests should be taken to promote the rational use of antimicrobial agents in clinical practice.