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作者将5周龄家兔分低钙组(0.4%)和正常钙组(16%)喂养,于第8周时分为5组,分别按每公斤体重O(对照)、5和15毫克将氟化钠注入实验兔腹腔内,观察血及尿中氟离子、血清总钙及钙离子和血糖的波动情况。发现血清总钙量及钙离子水平在注射氟后明显下降,低钙组比正常钙组的下降更为明显,且恢复较慢;注射氟后,低钙组的血糖明显高于正常钙组,恢复也有延迟现象;两种不同氟量中,以注射15毫克氟后血钙及血糖升高迅速而显著。两组血清氟在达到最高浓度的时间量上无差异,但氟从血中的清除速率却显然不同。在低钙组,所注射的氟大量潴留在血清
The authors fed 5-week-old rabbits into low-calcium group (0.4%) and normal calcium group (16%), divided into 5 groups on the 8th week. Sodium was infused into the abdominal cavity of experimental rabbits to observe the fluctuations of fluoride, total serum calcium, calcium and blood glucose in blood and urine. Found that serum total calcium and calcium levels decreased significantly after injection of fluorine, low-calcium group decreased more significantly than the normal calcium group, and slower recovery; injection of fluorine, low-calcium group was significantly higher than normal blood glucose group, Recovery also delayed; two different fluoride levels, after injection of 15 mg fluorine calcium and blood sugar increased rapidly and significantly. There was no difference in the amount of serum fluorine between the two groups in reaching the highest concentration, but the rates of fluorine clearance from the blood were apparently different. In the low-calcium group, the injected fluorine remained in the serum in large quantities