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目的:经皮冠状动脉介入治疗(PCI)前TIMI-3级血流对急性心肌梗死(AMI)患者的预后有益。本研究旨在探讨PCI前TIMI-3级血流的预测因子。方法:145例急诊PCI的AMI患者分为2组:TIMI3组(40例),PCI前TIMI-3级血流的患者;TIMI2组(105例),PCI前TIMI-0-2级血流的患者。监测2组的基础临床资料和短期预后。结果:TIMI3组的中性粒细胞计数和中性粒细胞/淋巴细胞(N/L)比值明显低于TIMI2组,Lo-gistic回归分析发现,中性粒细胞计数(OR,0.76,P=0.04)和N/L比值(OR,0.84,P=0.01)是TIMI3级血流的预测因子。结论:中性粒细胞和N/L比值是PCI前TIMI-3级血流的独立预测因素。
OBJECTIVE: TIMI-3 grade blood flow before percutaneous coronary intervention (PCI) is of benefit in the prognosis of patients with acute myocardial infarction (AMI). This study aimed to investigate the predictors of TIMI-3 grade pre-PCI blood flow. Methods: A total of 145 AMI patients with acute PCI were divided into two groups: TIMI3 group (40 cases), TIMI-3 grade before PCI; TIMI2 group (105 cases), TIMI-0-2 grade before PCI patient. The basic clinical data and short-term prognosis of the two groups were monitored. Results: The ratio of neutrophil and neutrophil / lymphocyte (N / L) in TIMI3 group was significantly lower than that in TIMI2 group. Lo-gistic regression analysis showed that the neutrophil count (OR, 0.76, P = 0.04 ) And N / L ratio (OR, 0.84, P = 0.01) were predictors of TIMI grade 3 blood flow. CONCLUSIONS: Neutrophil and N / L ratios are independent predictors of TIMI-3 grade pre-PCI blood flow.