耙向制剂治疗类风湿关节炎的研究进展

来源 :医药导报 | 被引量 : 0次 | 上传用户：leezhenghui

【摘要】

：

类风湿关节炎(RA)是一种多关节慢性自身免疫性疾病.表现为严重的软骨破坏和大量炎症细胞浸润,最终诱发全身并发症、残疾,使生活质量下降.目前临床治疗RA的药物存在剂量大、给

【作者】

：

苏慧李成

【机构】

：

延边大学药学院,延吉133000;延边大学附属医院药学部,延吉133000

【出处】

：

医药导报

【发表日期】

：

2020年12期

【关键词】

：

靶向制剂类风湿关节炎自身免疫性疾病纳米技术

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类风湿关节炎(RA)是一种多关节慢性自身免疫性疾病.表现为严重的软骨破坏和大量炎症细胞浸润,最终诱发全身并发症、残疾,使生活质量下降.目前临床治疗RA的药物存在剂量大、给药频繁、不良反应严重等缺点.这些局限性极大地促进了靶向制剂在RA治疗中的研究和应用.该文综述了靶向药物治疗RA的不良反应研究进展,讨论各种靶向策略的应用,阐明需要解决的挑战和对未来的展望.

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耙向制剂治疗类风湿关节炎的研究进展

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