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美国新奥尔良消息:在最近召开的美国皮肤病学研究院年会上宣布,一种对严重而难治的牛皮癣有很好疗效的维生素A衍生物已获准在美国使用。临床研究表明,这种新维生素A酸对90％以上的严重牛皮癣患者有益,在有些情况下甚至可以完全消除这种病。维甲酸乙酯(Etretinate)似乎对治疗红色、鳞屑状红皮牛皮癣患者和脓疱样牛皮癣患者特别有效。但缺点是此药能引起严重的生育缺陷、血脂增加、良性颅内高压、肝炎和骨肥厚。因此,此药只限于局部或口服皮质类固醇
NEW ORLEANS, USA - At the recent annual meeting of the American Academy of Dermatology, a vitamin A derivative that has been shown to be effective in the treatment of severe and refractory psoriasis has been approved for use in the United States. Clinical studies have shown that this new vitamin A acid in 90% of patients with severe psoriasis benefit, and in some cases can even completely eliminate the disease. Etretinate appears to be particularly effective in treating red, scale-like erythrodermic psoriasis patients and pustular psoriasis patients. But the disadvantage is that this medicine can cause serious childbirth defects, increased blood lipids, benign intracranial hypertension, hepatitis and bone hypertrophy. Therefore, this medicine is limited to topical or oral corticosteroids