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TAT皮试引起严重荨麻诊及TAT注后第五日出现迟发性过敏性皮疹较为少见,现将我院1990年门诊所遇的2例报告如下例1 男,21岁。既往有药物过敏史,对青霉素、氨基比林过敏。1990年8月30日因足部被生锈铁钉刺伤,局部伤口双氧水清洗消毒处理后,肌生TAT1500u预防破伤风。TAT皮试15分钟后,于皮试处先出现浅红色丘疹,继而面部、胸部皮肤发痒,有灼热感,出现少许浅红色斑丘疹。考虑为“TAT过敏”。即停用TAT,给予肌注地塞米松5mg,口服苯海拉明25mg tid,10分钟后皮疹渐消退。次晨,自手臂至躯干、面部出现较前一天更多更广泛的荨麻疹,浅红色,边缘不清,奇痒。肌注地塞米松5mg,20分钟后仍不见消退,且感胸闷、憋气。查体温36.5℃,脉搏
TAT skin test caused by serious nettle diagnosis and TAT after the fifth day appeared delayed allergic rash is rare, now our hospital in 1990 encountered two cases of outpatient cases as follows 1 male, 21 years old. Past history of drug allergy, allergy to penicillin, aminopyrine. August 30, 1990 due to foot rusty nail stab wounds, local wounds after hydrogen peroxide cleaning and disinfection, the mycoplasma TAT1500u prevent tetanus. TAT skin test 15 minutes later, in the skin test at first appeared light red papules, then facial, chest skin itching, burning sensation, a little light red rash. Consider “TAT allergy.” That is to disable the TAT, intramuscular dexamethasone given 5mg, diphenhydramine 25mg tid, 10 minutes after the rash subsided. The next morning, from the arm to the trunk, the face appeared more and more extensive urticaria than the previous day, light red, unclear edge, itching. Intramuscular dexamethasone 5mg, after 20 minutes still not subsided, and feeling chest tightness, suffocation. Check body temperature 36.5 ℃, pulse