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目的探讨药物治疗异位妊娠成败的相关因素,并寻找一种简单、有效、成功率高的药物治疗方法。方法对用氨甲蝶呤(MTX)和中药治疗的69例异位妊娠作回顾性分析与总结。结果孕龄≤45天,异位包块≤5cm,血β-hCG≤6000IU/L且无腹痛者,治疗成功率高于孕龄>45天,异位包块>5cm,β-hCG>6000IU/L且有腹痛者。成功率:腹腔镜下病灶注射MTX法为88.2%,单次肌肉注射MTX法为81.3%,服中药法为50%。结论孕龄、包块、β-hCG、腹痛是影响疗效的四大因素,严格掌握适应证是治疗成败的关键。单次肌肉注射MTX是一种简单、有效、成功率高的药物治疗方法。
Objective To explore the related factors of drug treatment for the success or failure of ectopic pregnancy and to find a simple, effective, high success rate of drug treatment. Methods Retrospective analysis and summary of 69 cases of ectopic pregnancy treated with methotrexate (MTX) and Chinese herbs. Results The gestational age ≤ 45 days, ectopic mass≤5cm, blood β-hCG≤6000IU / L and no abdominal pain, the success rate was higher than gestational age> 45 days, ectopic mass> 5cm, β-hCG> 6000IU / L and abdominal pain. Success rate: laparoscopic lesions injection MTX was 88.2%, a single intramuscular injection of MTX was 81.3%, taking traditional Chinese medicine method was 50%. Conclusion The gestational age, mass, β-hCG and abdominal pain are the four major factors affecting the curative effect. To master the indications strictly is the key to the success or failure of treatment. A single intramuscular injection of MTX is a simple, effective, high success rate of drug treatment.