论文部分内容阅读
测定了２９例口腔颌面部肿瘤患者的自然杀伤细胞（ＮＫ）活性及血清可溶性白细胞介素Ⅱ受体（ｓＩＬ－２Ｒ_α）的水平，结果表明：口腔颌面部恶性肿瘤患者的ＮＫ活性明显低于正常人（Ｐ＜０．０１）和口腔颌面部良性肿瘤患者（Ｐ＜０．０１），恶性肿瘤组血清ｓＩＬ－２Ｒ_α水平又明显高于良性肿瘤组（Ｐ＜０．０１）和正常对照组（Ｐ＜０．０１），且恶性肿瘤组ＮＫ活性与血清ｓＩＬ－２Ｒ_α水平呈负相关（ｒ＝－０．９３５，Ｐ＜０．０１），提示：ｓＩＬ－２Ｒ_α、ＮＫ活性可作为监测口腔颌面部恶性肿瘤病人免疫功能的指标。
The natural killer (NK) activity and soluble interleukin 2 receptor (sIL-2R_α) levels were measured in 29 patients with oral and maxillofacial tumors. The results showed that NK activity was significantly lower in patients with oral and maxillofacial malignancies Serum levels of sIL-2R_α in malignant tumors were significantly higher than those in benign tumors (P <0.01) and normal controls (P <0.01) and in patients with oral and maxillofacial benign tumors (P <0.01) (R = -0.935, P <0.01), suggesting that the activity of sIL-2R_α and NK could be used as the control group (P0.01), and the activity of NK in malignant tumor group was negatively correlated with the level of serum sIL- Indicators of Immune Function in Patients with Oral and Maxillofacial Malignancies.