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例1颜××,男,24岁。1983年10月27日以疟疾收住院。入院后除抗疟治疗外,因诉“胃痛”加服胃复安10mg,每日3次,10月28日下午6时胃区胀痛、恶心、呕吐一次,当班医生即给胃复安注射液10mg肌注,7时许病人出现全身阵发性强直性抽搐,先从左腿开始向上延伸至腹部、颈部;之后,病人出现颈部强硬、头向右侧歪斜、口角流涎、舌根向后回缩、舌运动障碍、语言不清、双下肢呈阵发性强直性抽搐、肌张力增高。心肺正常。肝脾不大。其它检查及神经系统检查均未见异常。诊断为胃复安所致锥体外系反应。当即停用胃复安,并即肌注654-2 10mg,并以50％葡萄糖40ml加10％葡萄糖酸钙10ml静脉缓慢推注。经上述处理后1.5小时症
Example 1 Yan × ×, male, 24 years old. October 27, 1983 to malaria hospital. In addition to anti-malarial treatment after admission, due to v. “Stomach pain” plus service metoclopramide 10mg, 3 times a day, at 28 o’clock on the October 28 stomach pain, nausea, vomiting once, Liquid 10mg intramuscular injection, at 7 am the patient had paroxysmal tonic convulsions, starting from the left leg began to extend up to the abdomen, neck; after the patient appeared stiff neck, head to the right skew, mouth drooling, tongue base After retraction, tongue dyskinesia, unclear language, both lower extremities were paroxysmal twitch, muscle tension increased. Cardiopulmonary normal. Small spleen and liver. Other tests and neurological examination showed no abnormalities. Diagnosis of metoclopramide induced extrapyramidal reactions. Immediate withdrawal of metoclopidine and intramuscular injection of 654-2 10mg, and 50% glucose 40ml plus 10% calcium gluconate 10ml intravenous bolus injection. 1.5 hours after the above treatment