Genetic assessment of inbred chicken lines indicates genomic signatures of resistance to Marek’s dis

• 作 者: Lingyang Xu Yanghua He Yi Ding
• 机 构: DepartmentofAnimal&,AvianSciences,AnimalGenomicsandImprovementLaboratory,LaboratoryofMolecularBio
• 出 处: 畜牧与生物技术杂志:英文版
• 发表日期: 2018年4期
• 关键词: GENETIC structure GENOMIC signature HOMOZYGOSITY Marek’s disease Recombinant CON
• 基金项目: U.S.Department of Agriculture(USDA)-Nation Research Initiative/National Institute of Food and Agriculture(NRI/NIFA)2008–35204-04660,2010–65205-20588 and 2011–67015-30183.

Background:Marek’s disease(MD)is a highly contagious pathogenic and oncogenic disease primarily affecting chickens.However,the mechanisms of genetic resistance for MD are complex and not fully understood.MD-resistant line 63 and MD-susceptible line 72 are