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目的探讨血清单胺氧化酶(MAO)的活性联合肝纤维化四项在肝硬化早期诊断中的临床价值。方法选取90例住院治疗的肝硬化患者作为观察组,选取90例同期进行健康体检的健康者作为对照组。运用速率法、放射免疫法来检测两组受试者血清中的MAO、肝纤维化四项的含量。结果观察组MAO活性、肝纤维化四项的含量高于对照组,差异均具有统计学上意义(P<0.05);MAO活性与肝纤维化四项的含量呈正相关。结论血清中的MAO活性联合肝纤维化四项含量可反映出肝纤维化的程度,且存在较好的相关性。相比MAO的敏感性更高,操作简便,利于在临床上推广应用。
Objective To investigate the clinical value of serum monoamine oxidase (MAO) activity combined with liver fibrosis in the early diagnosis of cirrhosis. Methods Ninety hospitalized cirrhotic patients were selected as the observation group, and 90 healthy people were selected as the control group during the same period. Using the rate method, radioimmunoassay to detect two groups of subjects serum MAO, liver fibrosis four items. Results The contents of MAO activity and liver fibrosis in the observation group were higher than those in the control group (P <0.05). The activity of MAO was positively correlated with the content of four items of liver fibrosis. Conclusion Serum MAO activity combined with four levels of liver fibrosis can reflect the degree of liver fibrosis, and there is a good correlation. Compared with the higher sensitivity of MAO, easy to operate, which is conducive to the clinical application.