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目的探讨瘤腔内注射平阳霉素联合介入栓塞治疗颌面部蔓状血管瘤的疗效。方法收集长春市儿童医院2011年7月至2015年7月收治的60例颌面部蔓状血管瘤患者,根据抽签法分为对照组和试验组,每组30例,对照组采取瘤腔内注射平阳霉素治疗,试验组采取介入栓塞联合瘤腔内注射平阳霉素治疗,观察2组患者的临床疗效及并发症情况。结果试验组治疗的总有效率96.67%(29/30)高于对照组的80.00%(24/30),2组相比差异显著(P<0.05);试验组的总并发症率为16.67%(5/30),对照组的总并发症率为20.00%(6/30),2组比较无显著差异(P>0.05)。结论瘤腔内注射平阳霉素联合介入栓塞治疗颌面部蔓状血管瘤的疗效显著,安全性高,创伤小,利于患者恢复。
Objective To investigate the efficacy of intratumoral injection of pingyangmycin combined with interventional embolization in the treatment of maxillofacial hemangiomas. Methods Sixty patients with maxillofacial hemangiomas from July 2011 to July 2015 in Changchun Children’s Hospital were divided into control group and experimental group according to the drawing method, 30 cases in each group. The control group was treated by intra-tumor Injection Pingyangmycin treatment, the experimental group to take interventional embolization and intratumoral injection of pingyangmycin treatment, the clinical efficacy and complications of two groups were observed. Results The total effective rate of the experimental group was 96.67% (29/30), which was significantly higher than that of the control group (80.00%, 24/30) (P <0.05). The total complication rate of the experimental group was 16.67% (5/30). The total complication rate in the control group was 20.00% (6/30). There was no significant difference between the two groups (P> 0.05). Conclusions The intraluminal injection of pingyangmycin combined with interventional embolization has significant curative effect on maxillofacial hemangiomas, which is safe, less traumatic and conducive to recovery.