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目的了解浙江省艾滋病病毒Ⅰ型(HIV-1)抗体阳性夫妻的流行病学特征,为预防该人群HIV感染和传播提供依据。方法利用浙江省1990-2006年艾滋病疫情资料,对其中HIV-1抗体阳性夫妻的流行病学特征进行分析。结果1990-2006年,全省共报告117对(234例)HIV-1抗体阳性的夫妻。其中农民或农民工占52.1%,主要是婚外异性性行为和婚内性行为感染,分别占38.5%和37.6%。一方有高危行为,另一方只有婚内性行为的夫妻占76.1%。38.5%的感染夫妻通过临床可疑检测发现。发现11例经母婴传播感染儿童。结论一方婚外性行为感染后经夫妻间性传播,是浙江省HIV-1抗体阳性夫妻感染和传播的主要方式。需要采取措施加强农村流动人群的高危性行为干预,促进一方感染后的及时检测发现和夫妻间行为干预,减少该人群的感染来源和家庭内的传播。
Objective To understand the epidemiological characteristics of HIV-1 positive couples in Zhejiang Province, and to provide basis for prevention of HIV infection and transmission in this population. Methods The epidemiological characteristics of HIV-1-positive couples in Zhejiang Province were analyzed from the data of AIDS epidemic in Zhejiang Province from 1990 to 2006. Results A total of 117 (234) HIV-1 positive couples were reported from 1990 to 2006 in the province. Among them, 52.1% were farmers or migrant workers, mainly being heterosexual and extra-marital sexes, accounting for 38.5% and 37.6% respectively. One party has high-risk behavior, while the other has only 76.1% of marital sex couples. 38.5% infected couples found through clinical suspicious tests. Eleven cases of mother-to-child transmission of infection were found. Conclusion One of the main causes of infection and transmission of HIV-1 antibody-positive couples in Zhejiang province after sexual intercourse was sexually transmitted through couples. Measures need to be taken to strengthen high-risk sexual intercourse among rural migrants and to facilitate timely detection and detection of inter-marital behavioral interventions and the transmission of infection within the family after one infection.