High fat diet dysregulates microRNA-17-5p and triggers retinal inflammation: Role of endoplasmic-ret

• 作 者: Maha Coucha Islam N Mohamed Sa
• 机 构: ClinicalandExperimentalTherapeutics
• 出 处: 世界糖尿病杂志：英文版（电子版）
• 发表日期: 2017年2期
• 关键词: 高胖的饮食 PALMITATE Endoplasmic-reticulum-stress 发炎 交往 Thioredoxin 蛋白质 Micro-RNA 17-

AIM To elucidate how high diet-induced endoplasmic reticulum-stress upregulates thioredoxin interacting protein expression in Müller cells leading to retinal inflammation. METHODS Male C57Bl/J mice were fed either normal diet or 60% high fat diet for