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目的了解我院药品不良反应(ADR)发生的情况与特点,加强临床医生上报ADR的意识,减少ADR的发生。方法收集我院2008年上报的124例ADR报表,从ADR发生的一般情况、给药途径、药物种类、损害类型及临床表现等方面进行整理、汇总和分析。结果年龄19～40a,人群ADR发生率最高(占46.77%);抗感染药物ADR发生率最高(占60.48%);引起ADR的主要用药途径为静脉给药(占58.06%);ADR损害类型以皮肤及其附件为主(占45.97%);严重ADR占2.42%;ADR的转归中,124例ADR均治愈或好转。结论应加强医院ADR的报告和监测工作,充分利用医院ADR信息,提高药物临床使用的安全性。
Objective To understand the situation and characteristics of adverse drug reaction (ADR) in our hospital and to enhance the awareness of clinicians in reporting ADR and to reduce the occurrence of ADR. Methods A total of 124 cases of ADR reported in our hospital in 2008 were collected, summarized, analyzed and summarized from the general situation of ADR, the route of administration, the types of drugs, the types of injuries and the clinical manifestations. Results The age ranged from 19 to 40 years. The incidence of ADR in the population was the highest (46.77%), the incidence of ADR was the highest (60.48%), and the main route of ADR was intravenous (58.06%). (45.97%), severe ADR (2.42%), and 124 ADR were cured or improved in ADR. Conclusion The reporting and monitoring of ADR in hospitals should be strengthened to make full use of ADR information in hospitals to improve the safety of clinical use of drugs.