新疆三个民族高血压患者及正常人血清过氧化脂质含量分析

• 作 者: 李新立 何秉贤 朱徐 黄定 路则莲
• 出 处: 新疆医学院学报
• 发表日期: 1994年02期
• 关键词: 血清过氧化脂质 差异有显著性 有显著性差异 何秉贤 前列环素 无显著性差异 病理过程 自由基生物学 血浆脂蛋白 临床观察

作者测定了哈萨克族正常人１００例，高血压患者７０例；维吾尔族正常人２００例，高血压患者１００例；汉族正常人１６５例，高血压患者８０例血清中过氧化脂质（ＬＰＯ）含量。发现哈萨克族高血压患者ＬＰＯ含量比正常人显著增高，统计学处理有显著性差异（Ｐ＜０．０５）；维吾尔族高血压患者ＬＰＯ含量虽较正常人有增高，但无显著性差异（Ｐ＞０．０５）；汉族高血压患者ＬＰＯ含量比正常人亦显著增高，差异有显著性（Ｐ＜０．０５）。结果提示：ＬＰＯ可能参与高血压形成的病理过程。

The authors determined 100 normal Kazakhs, 70 hypertensive patients, 200 Uygur normal subjects, 100 hypertensive patients, 165 normal Han patients, and 80 hypertensive patients with serum lipid peroxidation (LPO) . Found that the LPO content of Kazakh patients with hypertension was significantly higher than that of normal controls (P <0.05), while the LPO content of Uyghur hypertension patients was higher than that of normal people (P <0.05), but no significant difference was found > 0.05). The level of LPO in Han patients with hypertension was significantly higher than that in normal people (P <0.05). The results suggest that: LPO may be involved in the pathogenesis of hypertension.