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目的了解四川省凉山地区静脉吸毒人群梅毒感染情况及相关危险因素。方法于2002年11月8日-29日,以社区为基础开展横断面研究调查静脉吸毒人群的人口学和性行为特征,对采集的血样进行梅毒抗体检测。在社区招募了379个静脉吸毒人员。结果静脉吸毒人群中梅毒感染率为15.3%(58/379)。在单因素卡方分析中,性别、教育年限、近1个月同非主要性伙伴非保护性性行为、近6个月性伙伴人数、近6个月同非主要性伙伴性行为频率、近6个月新的性伙伴人数同梅毒感染有统计学意义。在多因素Logistic回归模型分析中,民族(OR, 2.85; 95% CI, 1.55-5.25), 婚姻(OR, 1.94; 95% CI, 1.04-3.62) 和近6个月以性交为条件接受钱物(OR, 5.60; 95% CI, 2.65-11.85) 同梅毒感染有统计学意义。结论本研究结果显示近6个月以性交为条件接受钱物同梅毒感染有统计学意义。需加强静脉吸毒人群健康教育和行为干预措施来提高其安全性行为。
Objective To understand the syphilis infection and related risk factors among intravenous drug users in Liangshan area, Sichuan province. METHODS: From November 8 to November 29, 2002, community-based cross-sectional study was conducted to investigate the demographic and sexual characteristics of intravenous drug users. The collected blood samples were tested for syphilis antibodies. 379 intravenous drug users were recruited in the community. Results The prevalence of syphilis in intravenous drug users was 15.3% (58/379). In the univariate chi-square analysis, gender, educational years, unprotected sex with non-essential partners in the past month, number of sexual partners in the past 6 months, frequency of non-essential sexual partners in the past 6 months, The number of new sexual partners in 6 months was statistically significant with syphilis infection. In the multivariate logistic regression model, ethnic (OR, 2.85; 95% CI, 1.55-5.25), marital (OR, 1.94; 95% CI, 1.04-3.62) (OR, 5.60; 95% CI, 2.65-11.85) with syphilis infection was statistically significant. Conclusion The results of this study show that in the past 6 months, intercourse as a condition to accept the money with syphilis infection was statistically significant. Health education and behavioral interventions for intravenous drug users need to be strengthened to improve their safety behaviors.