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目的评价宫颈液基薄层细胞学(TCT)检查配合阴道镜检查对宫颈病变的诊断价值。方法2005年3月~2006年3月在妇科门诊114例行TCT配合阴道镜下活检组织学检查,对宫颈上皮内瘤变进行筛查,以组织学诊断为金标准,对结果进行分析。结果418例TCT检查中,异常涂片97例,行阴道镜检查及定位下活检114例。病理检查示CINⅠ35例,CINⅡ18例,CINⅢ8例,宫颈鳞癌4例;TCT检查示ASCUS38例,LTSL46例,HISL11例,宫颈鳞癌2例。阴道镜检查示CINⅠ28例,CINⅡ21例,CINⅢ7例。结论液基薄层细胞学检查(TCT)配合阴道镜下活检组织学检查能及时发现癌前病变。
Objective To evaluate the diagnostic value of cervical liquid-based thin-layer cytology (TCT) combined with colposcopy in the diagnosis of cervical lesions. Methods From March 2005 to March 2006, 114 patients underwent colposcopy biopsy histological examination in gynecology clinics to screen cervical intraepithelial neoplasia. The histological diagnosis was the gold standard, and the results were analyzed. Results In 418 cases of TCT, 97 cases were abnormal smear, colposcopy and 114 cases under biopsy. Pathological examination showed CINⅠ35 cases, CINⅡ18 cases, CINⅢ8 cases, cervical squamous cell carcinoma 4 cases; TCT examination showed ASCUS38 cases, LTSL46 cases, HISL11 cases, cervical squamous cell carcinoma in 2 cases. Colposcopy showed CIN Ⅰ 28 cases, CIN Ⅱ 21 cases, CIN Ⅲ 7 cases. Conclusion Liquid-based thin-layer cytology (TCT) with colposcopic biopsy can detect precancerous lesions in time.