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对8例C肽阴性的Ⅰ型糖尿病(IDDM)病人从24.00点到08.00点每30分钟测一次血糖浓度,同时受试者接受胰岛素输注(0.12mU/kg/分)以评价黎明现象。随机安排在22.30点,病人或只口服睡眠药或与睡眠药一起服用5.0mg甲溴东莨菪碱(一种抗胆碱能药物)。睡眠后的生长激素浓度高
Eight patients with C-peptide negative type 1 diabetes mellitus (IDDM) were tested for blood glucose every 30 minutes from 24.00 to 08.00, and subjects underwent insulin infusion (0.12 mU / kg / min) to assess dawn. At 22.30, the patient was randomized either to take the sleeping pills orally or to take 5.0 mg of scopolamine (an anticholinergic drug) together with the sleeping pills. High concentrations of growth hormone after sleep