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目的:探讨血液灌流治疗重症肝病的临床疗效。方法:对19例重症肝病患者在内科综合治疗的基础上施行树脂血液灌流(HP)术。结果:所有患者治疗后神经、精神症状均明显好转,肝性脑病症状改善,消化道症状减轻。血清检验多种毒素及炎性递质浓度降低。结论:重症肝病患者在适当的内科治疗基础上行树脂血液灌流术,可明显提高临床疗效,降低病死率。
Objective: To investigate the clinical effect of hemoperfusion on severe liver disease. Methods: Nineteen patients with severe liver disease were treated with resin hemoperfusion (HP) on the basis of comprehensive medical treatment. Results: After treatment, neurological and psychiatric symptoms were significantly improved in all patients. The symptoms of hepatic encephalopathy were improved and the symptoms of digestive tract were relieved. Serum test for a variety of toxins and inflammatory neurotransmitters concentration decreased. Conclusion: Patients with severe liver disease under the appropriate medical treatment based on resin hemoperfusion, can significantly improve the clinical efficacy and reduce mortality.