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曾试验醋酸棉酚和棉籽油乳剂对人精子运动的作用。Waller等(1980年)报道醋酸棉酚体外实验对人精子运动无影响,而本实验结果与之相反,10~(-3)M醋酸棉酚使精子运动完全消失,这种差异可能由于忽略了棉酚溶解性而造成,棉籽油乳剂也有抑制精子的作用,揭示这种天然的低毒性的棉籽油能用来作为一种阴道避孕剂。引言棉酚是从棉籽油中提取的一种多酚化合物。从动物试验和临床上健康男人服用结果已表明棉酚是一种有效的男性避孕药。长期
The effect of acetate gossypol and cottonseed oil emulsions on human sperm motility was tested. Waller et al. (1980) reported that in vitro experiments with gossypol acetate had no effect on human sperm motility. In contrast, the results of this experiment showed that 10 -3 M acetate gossypol completely abolished sperm motility, which may be due to neglect Gossypol solubility caused, cottonseed oil emulsion also inhibited the role of sperm, revealing this natural low toxicity cottonseed oil can be used as a vaginal contraceptives. Introduction Gossypol is a polyphenolic compound extracted from cottonseed oil. The results from animal experiments and clinically healthy men have shown that gossypol is a potent male contraceptive. long