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木文报道了测定叔胺类药物的一种新的分光光度法。实验基于抗坏血酸-醋酐试剂(简称AsAA试剂)与叔胺类药物互相反应,其主成物在273、310、495和685um处显示4个最大吸收,其中以273nm处的表观克分子吸收系数(3.85～5.35×10~4)最大,即最为灵敏。所研究之叔胺类化合物均在1～8μg/ml范围呈线性关系,伯胺、仲胺及季铵均不干扰。本法既可测定单个药
Wood reported a new spectrophotometric method for the determination of tertiary amines. The experiment was based on the reaction of ascorbic acid-acetic anhydride reagent (referred to as AsAA reagent) with tertiary amines. The major products showed four absorption peaks at 273, 310, 495 and 685um, and the apparent absorption coefficient at 273nm (3.85 ~ 5.35 × 10 ~ 4) the largest, that is, the most sensitive. The study of tertiary amines in the range of 1 ~ 8μg / ml showed a linear relationship, primary amine, secondary amine and quaternary ammonium did not interfere. This method can measure a single drug