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目的 探讨脑磁图在顽固性癫痫术前评估的价值。方法 术前对 5 1例顽固性癫痫患者行脑磁图、磁共振及视频脑电检查 ,结合术中皮层脑电图分别进行选择性海马杏仁核切除术、标准前颞叶切除术及致痫灶切除术等手术 ;并用脑磁图定位神经导航下手术切除致痫灶 2例 ,神经导航下海马杏仁核切除 2例。结果 术后发作完全停止的占 76 5 % ,发作减少 >75 %的占 11 8% ,发作减少>5 0 %的占 5 8% ,发作减少不足 5 0 %的占 5 8% ;脑磁图与视频脑电及皮层脑电图的定位符合率分别为 82 %和 96 % ;脑磁图对内侧颞叶癫痫的定位敏感性较差 ;脑磁图定位导航手术可在切除致痫灶的同时保护脑的重要结构。结论 脑磁图是一项灵敏的无创性癫痫灶定位方法 ,是癫痫外科术前评估中的一项技术突破
Objective To explore the value of magnetoencephalography in the preoperative assessment of intractable epilepsy. Methods Fifty-one patients with intractable epilepsy underwent preoperative neuromagnetic examination, magnetic resonance imaging and video-electroencephalography. Combined with intraoperative cortical electroencephalography, selective hippocampal amygdalotomy, standard anterior temporal lobe resection and epilepsy 2 cases of epileptogenic lesions were excised with neuromagnetism and 2 cases of hippocampus almond nucleus under neuro-navigation. Results The total number of postoperative seizures was 76.5%, the seizures decreased by 75%, the seizures decreased by 75%, the seizure decreased by> 50%, and the seizure decreased by less than 50%, accounting for 58% And video EEG and cortical EEG positioning accuracy of 82% and 96%; magnetoencephalography medial temporal lobe epilepsy positioning sensitivity is poor; magnetoencephalography positioning navigation surgery in the removal of epileptogenic lesions at the same time Protect the important structure of the brain. Conclusions Magnetoencephalography is a sensitive and noninvasive method of locating epileptic foci and is a technical breakthrough in the preoperative evaluation of epilepsy surgery