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目的：分析并探讨成人接种不同剂量乙肝疫苗的免疫效果。方法：选取。结果：低剂量组观察人群在首次接种后第1个月抗-HBs阳转率为15.55%。高剂量组观察人群在首次接种后第1个月抗-HBs阳转率为24.27%。不同剂量抗-HBs阳转率有显著差异，经统计学检验，差异具有统计学意义（P<0.05）。821例男性人群在首次接种后第1个月抗-HBs阳转率为12.06%。801例女性人群在首次接种后第1个月抗-HBs阳转率为28.09%。不同免疫后时间段女性抗-HBs阳转率明显高于男性。经统计学检验，差异具有统计学意义（P<0.05）。结论：采取相同疫苗接种措施，高剂量免疫效果更加显著，临床上值得推广。“,”objective: to analyze and discuss the adult doses of hepatitis b vaccine inoculation immune effect. Methods: to select. Results: the low dose group of observing the crowd within 1 months after the ifrst vaccination anti - HBs positive rate was 15.55%. High dose group to observe the crowd within 1 months after the ifrst vaccination anti - HBs positive rate was 24.27%. Different doses of anti - HBs Yang turn rate have signiifcant difference, the statistical test, statistically signiifcant difference (P < 0.05). 821 cases of male population within 1 months after the ifrst vaccination anti - HBs positive rate was 12.06%. 801 cases of female population in the ifrst month after inoculation for the ifrst time anti - HBs positive rate was 28.09%. After different immune period women anti - HBs Yang transfer rate is signiifcantly higher than male. By the statistical tests, statistically signiifcant difference (P < 0.05).