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目的：探索流感病毒的抗肿瘤作用。方法：通过用小白鼠肉瘤细胞（S180）接种昆明系小鼠而形成荷瘤小鼠，再注射流感病毒于荷瘤小鼠，观察其抑制肉瘤细胞生长情况。结果：活流感病毒注射后的抑瘤率达到58．20％，而PHA和5-氟脲嘧啶（5-FU）的抑瘤率分别为65．92％和59．06％，三者之间无显著性差异（P＞0．5）。结论：活流感病毒在试验动物体内具有抑制S180瘤细胞生长的作用。
Objective: To explore the anti-tumor effects of influenza virus. METHODS: Tumor-bearing mice were established by inoculating Kunming mice with mouse sarcoma cells (S180). Then influenza virus was injected into the tumor-bearing mice to observe the growth inhibition of sarcoma cells. Results: The inhibitory rate of live influenza virus reached 58.20% after injection, while the inhibition rates of PHA and 5-fluorouracil (5-FU) were 65.92% and 59.06%, respectively. No significant difference (P>0.5). Conclusion: Live influenza virus has the effect of inhibiting the growth of S180 tumor cells in experimental animals.