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目的 :探讨女性踏车运动试验前后校正QT间期的变化及意义。方法 :分析 14 5例行冠状动脉 (冠脉 )造影检查的女性患者亚极量踏车运动试验前后QTc的动态变化 ,计算以运动后即刻QTc较运动前QTc延长≥ 4 0ms作为运动试验阳性判断标准的临床价值 ,并与传统ST下移标准的临床价值进行对照。结果 :冠心病(CHD)组运动后即刻QTc与运动前QTc的差值 (即刻ΔQTc)较非CHD组显著增大 ,且随冠脉狭窄程度的加重而增大 ;以运动后即刻ΔQTc≥ 4 0ms作为运动试验阳性的判断标准 ,其特异性、敏感性、准确性分别为 90 .0 % (P<0 .0 5 )、88.7% (P <0 .0 1)、89.0 % (P <0 .0 1) ,显著优于传统的ST标准。结论 :女性CHD患者运动试验后QTc显著延长 ,运动后即刻ΔQTc≥ 4 0ms可作为女性运动试验阳性的判断标准 ,它有利于克服运动试验中ST标准对女性CHD患者误诊率高、假阳性率高的缺点
Objective: To investigate the changes of QT interval and its significance before and after the female treadmill exercise test. Methods: The dynamic changes of QTc before and after sub-maximal treadmill exercise test in 145 female patients undergoing coronary (coronary) coronary angiography were analyzed. The QTc QTc prolongation ≥ 4 ms before exercise was calculated as the positive test of exercise test Standard clinical value, and with the traditional clinical value of ST down the standard control. Results: The difference between QTc and QTc immediately after exercise in CHD group (immediate ΔQTc) was significantly higher than that in non-CHD group and increased with the severity of coronary stenosis. After the exercise, the value of ΔQTc ≥ 4 The specificity, sensitivity and accuracy of0 0ms as a positive test for exercise test were90.0% (P <0.05), 88.7% (P <0.01) and89.0% (P <0 .0 1), which is significantly better than the traditional ST standard. Conclusion: The QTc of female patients with CHD is significantly prolonged after exercise test, and ΔQTc≥4 0ms immediately after exercise can be regarded as the positive judgment criterion of female exercise test. It is helpful to overcome the high misdiagnosis rate and false positive rate of female CHD patients in ST test Shortcomings