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目的 :探讨原发性十二指肠恶性肿瘤的临床特点及其诊断。方法 :对 1 979年以来诊治的 37例原发性十二指肠恶性肿瘤的临床资料及随访结果进行回顾性分析。结果 :37例中 ,肿块位于十二指肠乳头周围者 2 9例。最常见的临床表现为腹痛、腹胀、黄疸、便血、呕血和腹部包块等。 37例均经手术治疗 ,术前诊断率为56 .7% (2 1 / 37) ,根治切除率为 62 .1 % (2 3/ 37) ,其中 31例获随访 ,死亡 2 2例 ,平均存活 (1 9± 8.1 )个月 ,存活9例。内镜检查的诊断符合率最高 ,为 75 % (1 2 / 1 6)。结论 :原发性十二指肠恶性肿瘤早期诊断较为困难 ,内镜是重要的诊断方法 ,改善病人预后的关键是加强对本病的重视和认识。
Objective: To investigate the clinical features and diagnosis of primary duodenal malignancies. Methods: The clinical data and follow-up results of 37 cases of primary duodenal malignancies diagnosed and treated since 1979 were retrospectively analyzed. Results: Of the 37 cases, 29 were located around the duodenal papilla. The most common clinical manifestations of abdominal pain, abdominal distension, jaundice, blood in the stool, hematemesis and abdominal mass. The 37 cases were treated by surgery. The preoperative diagnosis rate was 56.7% (21/37). The radical resection rate was 62.1% (2/37). Among them, 31 cases were followed up and 22 cases died. The mean Survival (19 ± 8.1) months, 9 cases of survival. Endoscopy diagnostic accuracy of the highest rate of 75% (12/16). Conclusion: The early diagnosis of primary duodenal malignant tumors is more difficult. Endoscopy is an important diagnostic method. The key to improve the prognosis of patients is to pay more attention to this disease.