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目的分析急性心肌梗死（ＡＭＩ）伴高血压患者的临床特征及卡托普利的影响。方法１４９６２例ＡＭＩ患者随机分为卡托普利组或安慰剂组，分析伴有或无高血压患者的临床特点。结果ＡＭＩ伴有高血压史者６０４６例，占总人数的４０．４％，男性占６９．４％。有高血压病史（ＨＨＴ）与无高血压史（ＮＨＴ）者平均年龄分别为６２．８±９．３，６０．２±１１．３岁；合并糖尿病史者分别为１２．８％，７．０％；合并陈旧性心肌梗死史者分别为１４．１％，１１．０％；基础收缩压分别为１３６．８±２６．２，１１９．４±２０．１ｍｍＨｇ；舒张压分别为８６．４±１５．７，７７．８±１２．７ｍｍＨｇ；随机治疗前心力衰竭发生率分别为２４．６％，１９．４％。ＨＨＴ、ＮＨＴ病人卡托普利治疗组与安慰剂组的基础临床特征相似。随机治疗４周，ＨＨＴ治疗组２８ｄ病死率（１０．３％）较安慰剂组（１１．６％）减少１１．２％（Ｐ＝０．１２），ＮＨＴ（８．２％ｖｓ８．５％）减少３．５％（Ｐ＝０．６８）；卡托普利组与安慰剂组比较，ＨＨＴ、ＮＨＴ心力衰竭发生率（１９．４％ｖｓ２１．１％；１５．５％ｖｓ１６．９％）分别减少８．１％（Ｐ＝０．０９），８．３％（Ｐ＝０．０７）；心室颤动（３?
Objective To analyze the clinical characteristics of patients with acute myocardial infarction (AMI) accompanied with hypertension and the influence of captopril. Methods A total of 14962 AMI patients were randomly divided into captopril group or placebo group, and the clinical features of patients with or without hypertension were analyzed. Results There were 6,046 AMI patients with history of hypertension, accounting for 40.4% of the total number of men and 69.4% of men. The average age of people with history of hypertension (HHT) and without history of hypertension (NHT) was 62.8 ± 9.3 and 60.2 ± 11.3 years old, respectively; those with history of diabetes mellitus were 12.8% and 7 respectively. 0% respectively; the history of AMI was 14.1% and 11.0% respectively; the systolic blood pressure was 136.8 ± 26.2 and 119.4 ± 20.1mmHg respectively; the diastolic blood pressure was 86.4 ± 15.7, 77.8 ± 12.7mmHg; incidence of heart failure before randomization were 24.6%, 19.4%. HHT, NHT patients Captopril treatment group and placebo group of basic clinical features similar. At 4 weeks of randomized treatment, the 28-day mortality (10.3%) in HHT-treated patients was 11.2% (P = 0.12) lower than in placebo patients (11.6%), with NHT (8.2% vs 8.5% ) Decreased by 3.5% (P = 0.68). Compared with placebo group, the incidences of heart failure in HHT and NHT group were significantly lower than those in placebo group (19.4% vs21.1%; 15.5% vs16.9% ) Decreased 8.1% (P = 0.09) and 8.3% (P = 0.07), respectively; and ventricular fibrillation (3?