论文部分内容阅读
骨质疏松症是一种全身性的骨代谢障碍性疾病,是以骨量减少、骨微结构退化、骨脆性增加及易发生骨折为特征的全身性疾病。骨质疏松症的发生与破骨细胞的骨吸收与成骨细胞的骨形成之间动态平衡的破坏密切相关。雌激素水平下降与骨质疏松发生发展关系密切。激素替代治疗是绝经后骨质疏松的重要治疗方案,以往认为雌激素的主要骨保护
Osteoporosis is a generalized disease of bone metabolism disorders, which is a systemic disease characterized by reduced bone mass, degenerated bone microarchitecture, increased bone fragility and prone to fracture. The occurrence of osteoporosis is closely related to the destruction of the homeostasis between osteoclast resorption and osteoblast formation. The decline of estrogen level is closely related to the occurrence and development of osteoporosis. Hormone replacement therapy is an important treatment for postmenopausal osteoporosis in the past that the main estrogen bone protection