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应用Wittig试剂与羰基化合物反应以合成烯类衍生物的研究,近年来有很大的进展。以砷代替磷所制成的Wittig类型的试剂与羰基化合物的反应,结果不完全相似;Henry等用亚甲基三苯基砷与二苯甲酮反应,找出除生成不对称二苯乙烯外,还生成二苯乙醛。他们认为后者的生成机理是先形成环氧化合物,然后异构化开环成醛:Johnson研究亚芴基三苯基胂与羰基化合物的反应,从几种醛可得到高产率的相应烯类衍生物,但与酮不起反应。
In recent years, great progress has been made in the study of the reaction of Wittig reagent with carbonyl compounds to synthesize alkene derivatives. Reactions of Wittig-type reagents with carbonyl compounds with arsenic instead of phosphorus did not completely resemble each other. Henry et al. Reacted with benzophenone by triphenylene arsenide to find that in addition to asymmetric stilbenes , But also generate benzophenone. They argue that the latter mechanism of formation is the formation of an epoxy compound followed by isomerisation of ring opening to aldehyde: Johnson’s study of the reaction of fluorenylidenetriphenylarsine with carbonyl compounds from which high yields of corresponding alkenes are obtained Derivatives, but not react with ketones.