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药物对眼的损伤作用,是一个值得高度重视的问题。在新药用于临床之前,必须注意检查其对眼的毒性。ERG作为视觉电生理的一种工具,为定量分析视网膜功能状态,提供了有效的客观手段,因此在眼科毒理学领域中日益受到重视。本文综述近年来应用ERG在眼毒理学中进行实验研究的概况,包括:整体动物的实验研究;在离体视网膜标本上的实验研究;细胞内记录ERG的实验研究。’。……
Drug damage to the eyes, is a problem worthy of great attention. In the new drug used in clinical, must pay attention to check its toxicity to the eye. As a tool of visual electrophysiology, ERG provides an effective and objective means for quantitative analysis of retinal functional status, and is therefore increasingly valued in the field of ophthalmology and toxicology. This review summarizes the recent advances in the use of ERG in eye toxicology research, including: experimental studies of whole animals; experimental studies on isolated retinal specimens; and experimental studies of intracellular recording of ERG. ’. ...