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在重症监护病房中呼吸机相关性肺炎 (VAP)是最重要和最常见的感染并发症。新近发现的 β防御素 2 (BD 2 )主要分布于皮肤和呼吸道上皮细胞 ,是具有广谱高效抗菌作用的小分子抗菌肽 ,在机体的免疫炎症反应中发挥重要作用。本研究观察大鼠VAP模型中肺组织BD 2的基因和蛋白表达水
Ventilator-associated pneumonia (VAP) is the most important and common infection complication in the intensive care unit. The newly discovered β-defensin 2 (BD 2) is mainly distributed in the skin and respiratory epithelial cells. It is a small-molecule antimicrobial peptide with broad-spectrum antibacterial activity and plays an important role in the immune and inflammatory response in the body. This study was to investigate the gene and protein expression of BD 2 in rat lung VAP model