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目的：探讨危重型脑出血预后与局部自由基浓度的方法：对危重型脑出血行ＣＴ 引导下血肿抽吸引流并侧脑室引流，设计对照组单管血肿抽吸引流，同时分别测定血清、血肿及脑脊液内丙二醛（ＭＤＡ）及超氧化物歧化酶（ＳＯＤ）总活力。结果：血肿及脑脊液内局部ＭＤＡ 及ＳＯＤ水平均明显高于血清（Ｐ均＜ ０．０１）；双管引流术的临床疗效明显优于单管引流（Ｐ＜ ０．０１），但ＳＯＤ及ＭＤＡ 水平无差异（Ｐ均＞ ０．０５）。结论：脑损伤局部高自由基水平是病情严重程度的指标之一；双管引流法能明显缩短患者清醒时间，提高生活能力
Objective: To explore the prognosis of severe intracerebral hemorrhage and the concentration of local free radicals: CT-guided hematoma drainage and lateral ventricle drainage in critically ill patients with intracerebral hemorrhage. The control group was treated by single-tube hematoma aspiration and drainage. Serum and hematoma And cerebrospinal fluid malondialdehyde (MDA) and superoxide dismutase (SOD) total activity. Results: The levels of MDA and SOD in hematoma and cerebrospinal fluid were significantly higher than those in serum (P <0.01). The clinical curative effect of double-tube drainage was better than single-tube drainage (P <0.01) No difference in level (P> 0.05). Conclusion: The local high free radical level in brain injury is one of the indicators of the severity of the disease. The double-tube drainage method can significantly shorten the awake time and improve the living ability